"Dawson's
fingers" is the name for the lesions around the
ventricle-based brain veins of patients with multiple sclerosis. The condition
is thought to be the result of inflammation or mechanical damage by blood
pressure around long axis of medular veins.
Dawson's fingers spread
along, and from, large periventricular collecting veins, and are attributed to
perivenular inflammation.
Lesions far away from these
veins are known as Steiner's splashes.
Sometimes experimental
autoimmune encephalomyelitis has been triggered in humans by accident or
medical mistake. The damage in these cases fulfils all the pathological
diagnostic criteria of MS and can therefore be classified as MS in its own
right. The lesions were classified as pattern II in the Lucchinetti system.
This case of human EAE also showed Dawson fingers.
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